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刊物信息

期刊名称:药物分析杂志
主管单位:中国科学技术协会
主办单位:中国药学会
承办:中国食品药品检定研究院
主编:金少鸿
地址:北京天坛西里2号
邮政编码:100050
电话:010-67012819,67058427
电子邮箱:ywfx@nifdc.org.cn
国际标准刊号:ISSN 0254-1793
国内统一刊号:CN 11-2224/R
邮发代号:2-237
 

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Fisher成分分析法用于决明子化学指纹特征相似性研究

Application of Fisher component analysis in the research of chemical fingerprint feature similarities of Semen Cassiae

作者: 鄢海燕, 邹纯才 
作者(英文):YAN Hai-yan, ZOU Chun-cai
分类号:
出版年·卷·期(页码):2012,32 (8):0-0
DOI: 10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------

目的: 探求Fisher成分分析法用于大、小决明子化学指纹特征相似的研究,为大、小决明子的分类提供依据。 方法: 对获得的指纹图谱进行数字化处理并得到大、小决明子的标准指纹图谱,然后用Fisher成分分析法提取大、小决明子化学指纹图谱中的隐含化学特征,对大、小决明子进行质量模式分类,并与主成分分析法及标准图谱法进行分类效果对比研究。 结果: Fisher成分分析法能更好地表征大、小决明子的化学模式特征,分类准确性高。 结论: 根据Fisher成分分析法可识别大、小决明子的化学指纹特征的内在差异,可用于鉴别中药材真伪。

-----英文摘要:---------------------------------------------------------------------------------------

Objective: To explore whether Fisher component analysis can be used in the research of chemical fingerprint feature similarities of Semen Cassiae Obtasefolia and Semen Cassia Tora, and to provide a basis for the classification of Semen Cassiae. Methods: The standard fingerprints of Semen Cassiae obtasefolia and Semen Cassia tora were obtained by digitizing their original fingerprints.Next,the chemical fingerprint features of Semen Cassiae obtasefolia and Semen Cassia tora were extracted Fisher component analysis.Then,Semen Cassiae obtasefolia and Semen Cassia tora were classified by quality model.The classification results were compared with those classified by quality model.The classification results were compared with those classified by principal component analysis and standard atlas analysis. Results: Fisher component analysis could show the chemical pattern feature of Semen Cassiae obtasefolia and Semen Cassia tora more effectively with high classification precision. Conclusion: Fisher component analysis can be used in identifying the internal differences of Semen Cassiae obtasefolia and Semen Cassia tora in chemical fingerprint features and the authenticity of Chinese medicinal.

-----参考文献:---------------------------------------------------------------------------------------
1 CHEN Min-jun(陈闽军),QU Hai-bin(瞿海斌),CHENG Yi-yu(程翼宇).Identifying the authenticity of Chinese medicinal material with chemical fingerprint features(一类用化学指纹特征鉴别中药材真伪的方法).Chem J Chin Univ (高等学校化学学报),2003,24(12):2181
2 ZHONG Jing-hua(钟敬华),HOU Xiao-rong(侯晓蓉),FAN Xiao-hui(范骁辉).Sort similarity based on computational method for chemical fingerprinting(化学指纹图谱类别相似性计算方法研究).China J Chin Mater Med (中国中药杂志),2010,35(4):477
3 ZOU Chun-cai(邹纯才),YAN Hai-yan(鄢海燕).Chromatographic Fingerprints of Traditional Chinese Medicine and Its Digital(中药指纹图谱及其数字化).Hefei(合肥):Anhui Science & Technology Publishing House(安徽科学技术出版社),2008.98
4 YAN Hai-yan(鄢海燕),ZOU Chun-cai(邹纯才),FANG Hong-zhuang(方洪壮).Study of HPLC profiles in crude and processed seeds of Cassia Tora(决明子生品及炮制品的HPLC指纹特征研究).China Pharm(中国药房),2009,20(3):204
5 SUN Guo-xiang(孙国祥),YU Xiu-ming(于秀明),WANG Jia-qing(王佳庆).Study on the digitized HPLC fingerprints of Ciwujia injection (刺五加注射液HPLC数字化指纹图谱研究).Chin J Pharm Anal(药物分析杂志),2009,29 (3):356
6 SUN Guo-xiang(孙国祥),HU Yue-shan(胡玥珊),ZHANG Chun-ling(张春玲),et al. Study on construction of traditional Chinese medic ine digitized fingerprints(构建中药数字化指纹图谱研究).Chin J Pharm Anal(药物分析杂志),2009,29 (1):160
7 ZOU Chun-cai(邹纯才),YAN Hai-yan(鄢海燕),FANG Hong-zhuang(方洪壮).Realization and application of fingerprint database system of Semen Cassiae(决明子指纹图谱数据库的实现与应用).Comput Appl Chem (计算机与应用化学),2008,25(4):494

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