关闭
 
读者在线:用户名 密码
首页 期刊简介 投稿须知 期刊目录 专家风采 编委会 特邀顾问 联系我们 移动出版
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5



刊物信息

期刊名称:药物分析杂志
主管单位:中国科学技术协会
主办单位:中国药学会
承办:中国食品药品检定研究院
主编:金少鸿
地址:北京天坛西里2号
邮政编码:100050
电话:010-67012819,67058427
电子邮箱:ywfx@nifdc.org.cn
国际标准刊号:ISSN 0254-1793
国内统一刊号:CN 11-2224/R
邮发代号:2-237
 

访问统计
您是第  1 0 5 1 1 7 9 9 位浏览者
您当前的位置:首页 >> 正文

肝素钠中多硫酸软骨素的测定技术进展___

Progress on determination of oversulfated chondrointin sulfate in heparin

分类号:
出版年·卷·期(页码):2010,30 (2):0-0
DOI: 10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------


本文对多硫酸软骨素的相关性质及测定肝素钠中多硫酸软骨素的方法进行了综述。

-----英文摘要:---------------------------------------------------------------------------------------

In this paper,correlative properties and determination of OSCS in heparin are reviewed.

-----参考文献:---------------------------------------------------------------------------------------
1Longstaff C,Whitton CM,Stebbings R,et al.How do we assure the quality of biological medicines.Drug Discov Today,2009,14(1-2):50
2Kishimoto TK,Viswanathan K,Ganguly T,et al.Contaminated heparin associated with adverse clinical events and activation of the contact system.N Engl J Med,2008,358(23):2457
3http://www.fda.gov/cder/drug/infopage/heparin/heparin_CE_method
4http://www.fda.gov/cder/drug/infopage/heparin/Heparin_NM_method
5Bairstow S,McKee J,Nordhaus M,et al.Identification of a simple,sensitive microplate method for the detection of over-sulfated chondroitin sulfate in heparin products.Anal Biochem,2009,388(2):317
6Maruyama T,Toida T,Imanari T,et al.Conformational changes and anticoagulant activity of chondroitin sulfate following its O-sulfonation.Carbohydr Res,1998,306(1-2):35
7Clark M,Hoppensteadt D,Walenga J,et al.Molecular profiling of heparinase-I resistant glycosaminoglycans in contaminated heparins.Comparative studies with uncontaminated heparin and porcine oversulfated chondroitin sulfate.Angiol,2008,27(5):370
8Volpi N,Maccari F.Electrophoretic approaches to the analysis of complex polysaccharides.J Chromatogr B Analyt Technol Biomed Life Sci, 2006,834(1-2):1
9Domanig R,J bstl W,Gruber S,et al.One-dimensional cellulose acetate plate electrophoresis--A feasible method for analysis of dermatan sulfate and other glycosaminoglycan impurities in pharmaceutical heparin.J Pharm Biomed Anal,2009,49(1):151
10Volpi N,Maccari F,Linhardt RJ.Capillary electrophoresis of complex natural polysaccharides.Electrophoresis,2008,29(15):3095
11Simonet BM,R os A,Grases F,et al.Determination of myo-inositol phosphates in food samples by flow injection-capillary zone electrophoresis.Electrophoresis,2003,24(12-13):2092
12Wielgos T,Havel K,Ivanova N,et al.Determination of impurities in heparin by capillary electrophoresis using high molarity phosphate buffers.J Pharm Biomed Anal,2009,49(2):319
13Volpi N,Maccari F,Linhardt RJ.Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations.Anal Biochem,2009,388(1):140
14Somsen GW,Tak YH,Tora o JS,et al.Determination of oversulfated chondroitin sulfate and dermatan sulfate impurities in heparin by capillary electrophoresis.J Chromatogr A,2009,1216(18):4107
15Norwig J, Beyer T, Brinz D,et al.Prediction of the oversulphated chondroitin sulphate contamination of unfractionated heparin by ATR-IR spectrophotometry.Pharm Sci Notes,2009,1:17
16Spencer JA,Kauffman JF,Reepmeyer JC,et al.Screening of heparin API by near infrared reflectance and Raman spectroscopy.J Pharm Sci,2009,98(10):3540
17Toida T,Huang Y,Washio Y,et al.Chemical microdetermination of heparin in plasma.Anal Biochem,1997,251(2):219
18Sugahara K,Tsuda H,Yoshida K,et al.Structure determination of the octa-and decasaccharide sequences isolated from the carbohydrate-protein linkage region of porcine intestinal heparin. J Biol Chem,1995,270(39):22914
19Holme KR,Perlin AS.Nuclear magnetic resonance spectra of heparin in admixture with dermatan sulfate and other glycosaminoglycans.2-D spectra of the chondroitin sulfates.Carbohydr Res,1989,186(2):301
20Atha DH,Coxon B,Reipa V,et al.Physiochemical characterization of low molecular weight heparin.J Pharm Sci,1995,84(3):360
21McEwen I,Rundl f T,Marianne Ek,et al.Effect of Ca2+ on the 1H NMR chemical shift of the methyl signal of oversulphated chondroitin sulphate,a contaminant in heparin.J Pharm Biomed Anal,2009,49(3):816
22Sitkowski J, Bednarek E, Bocian W,et al.Assessment of oversulfated chondroitin sulfate in low molecular weight and unfractioned heparins diffusion ordered nuclear magnetic resonance spectroscopy method.J Med Chem,2008,51(24):7663
23Beyer T,Diehl B,Randel G,et al.Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy.J Pharm Biomed Anal,2008,48(1):13
24Bigler P,Brenneisen R.Improved impurity fingerprinting of heparin by high resolution 1H NMR Spectroscopy.J Pharm Biomed Anal,2009,49(4):1060
25Walenga JM,Hoppensteadt DA.Monitoring the new antithrombotic drugs.Semin Thromb Hemost,2004,30(6):683
26Trehy ML,Reepmeyer JC,Kolinski RE,et al.Analysis of heparin sodium by SAX/HPLC for contaminants and impurities.J Pharm Biomed Anal,2009,49(3):670

欢迎阅读《药物分析杂志》!您是该文第 8206位读者!

药物分析杂志 © 2009
地址:北京天坛西里2号 邮政编码:100050; 电子邮件:ywfx@nicpbp.org.cn