牛磺酸滴眼液的渗透压考察及其影响因素分析
Studies on the osmotic pressure of Taurine Eye Drops and its affect factors
分类号:
出版年·卷·期(页码):2011,31 (3):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------
目的: 了解牛磺酸滴眼液的渗透压现状及处方组成对其影响情况。 方法: 采用SMC-30B渗透压摩尔浓度测定仪,采用冰点下降法对国内5个厂家牛磺酸滴眼液进行渗透压摩尔浓度测定。 结果: 多数牛磺酸滴眼液的渗透压均高出人眼可耐受的渗透压范围,处方组成的不合理是造成渗透压超标的主要因素。 结论: 牛磺酸滴眼液的渗透压现状亟待解决,其处方组成需要进一步研究改进。
-----英文摘要:---------------------------------------------------------------------------------------
Objective: In order to understand the current information about the osmotic pressure of taurine eye drops and the influence of components of the formulation. Method: Using SMC-30B osmotic pressure tester to measure the osmolality of taurine eye drops of the 5 factories by freezing-point depression method. Results: Most of the samples have higher osmotic pressure beyond the tolerance of human’s eyes, the unreasonable prescription is the main factor leading to the results. Conclusion: The situation of Taurine eye drops of osmotic pressure is urgently to be solved. Component of formulation needs to be further studied and improved.
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