GC-MS法对抗病毒口服液中挥发性成分的快速鉴定

目的: 分析鉴定抗病毒口服液中挥发性成分。 方法: 采用水蒸气蒸馏法从抗病毒口服液及其处方药材中提取挥发油,GC-MS法鉴定挥发油类成分。 结果: 抗病毒口服液中共检出28个色谱峰,鉴定22个化合物,并对其进行归属,占挥发油总量的93.51%,其中含量最高的是4-松油醇,约占总量的42.03%。 结论: 首次建立GC-MS法鉴定抗病毒口服液中挥发性成分,方法简便、快速、准确,为该制剂的质量控制提供依据。

Objective: To analyze the volatile constituents of Kangbingdu oral liquid. Methods: The volatile oil was extracted from Kangbingdu oral liquid and medicinal materials in prescription by warer-steam distillation method and separated by capillary column chromatography.The components were quantitatively determined with normalization method and identified by GC-MS. Results: 28 chromatografic peeks were detected and 22 compounds were identified and assigned,which were composed of 93.51% of the total essential oil.The highest constituent in essential oil was 4-terpineol,which was composed of 42.03% of the total essential oil. Conclusions: The GC-MS method to identify the essential oil of Kangbingdu oral liquid is reported for the first time.The established method is simple,rapid and accurate.The study provides basis for quality control of the preparation.