注射用兰索拉唑在健康受试者体内的药代动力学研究

[1] Horn J.The proton-pump inhibitors:similarities and differences[J]. Clin Ther, 2000, 22(3):266
[2] Maurel P.The use of adult human hepatocytes in primary culture and other in vitro systems to investigate drug metabolism in man[J].Adv Drug Deliv Rev, 1996, 22(1):105
[3] Takeda Pharmaceuticals American, Inc.PREVACID© I.V.-lansoprazole injection, powder, for solution[DB/OL].[2010-03].http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm HYPERLINK"http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm" ?archiveid=17961
[4] Song M, Gao X, Hang T, et al.Simultaneous determination of lansoprazole and its metabolites 5'-hydroxy lansoprazole and lansoprazole sulphone in human plasma by LC-MS/MS:application to a pharmacokinetic study in healthy volunteers[J].J Pharm Biomed Anal, 2008, 48(4):1181
[5] Wu GL, Zhou HL, Shentu JZ, et al.Determination of lansoprazole in human plasma by rapid resolution liquid chromatography-electrospray tandem mass spectrometry:application to a bioequivalence study on Chinese volunteers[J].J Pharmacokinet Biopharm, 2008, 48(5):1485
[6] Oliveira CH, Barrientos-Astigarraga RE, Abib E, et al. Lansoprazole quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry[J]. J Chromatogr B, 2003, 783(2):453
[7] Pandya KK, Mody VD, Satia M C, et al.High-performance thin-layer chromatographic method for the detection and determination of lansoprazole in human plasma and its use in pharmacokinetic studies[J].J Chromatogr B, 1997, 693(1):199
[8] Zhang D, Zhang Y, Liu M, et al.Pharmacokinetics of lansoprazole and its main metabolites after single and multiple intravenous doses in healthy Chinese subjects[J].Eur J Drug Metab Pharmacokinet, 2013, 38(3):209
[9] ZENG Xiao-hui(曾晓晖), SHI Lei(石磊), GUAN Hui(关慧), et al.Pharmacokinetics of lansoprazole and its metabolites between Chinese CYP2C19 Ems and PMs subjects (中国CYP2C19强代谢者和弱代谢者的兰索拉唑及其代谢产物的药代动力学)[J]. Clin J Clin Pharmacol(中国临床药理学杂志), 2013, 29(4):269
[10] Desta Z, Zhao X, Shin JG, et al.Clinical significance of the cytochrome P450 2C19 genetic polymorphism[J].Clin Pharmacokinet, 2002, 41(12):913
[11] Uno T, Yasui-Furukori N, Takahata T, et al.Determination of lansoprazole and two of its metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography:application to measuring CYP2C19 activity[J].J Chromatogr B, 2005, 816(1):309
[12] Miura M, Tada H, Suzuki T.Simultaneous determination of lansoprazole enantiomers and their metabolites in plasma by liquid chromatography with solid-phase extraction[J].J Chromatogr B, 2004, 804(2):389
[13] Hishinuma T, Suzuki K, Yamaguchi H, et al.Simple quantification of lansoprazole and rabeprazole concentrations in human serum by liquid chromatography/tandem mass spectrometry[J].J Chromatogr B, 2008, 870(1):38