款冬花非药用部位的生药学鉴别研究

目的：针对市场上出现的款冬花的非药用部位掺杂的现象，开展生药学鉴别研究，为款冬花及相关药材的质量控制提供参考依据。方法：在市场调查、植物采集，药材样本及馆藏标本的生药学研究基础上，对作为掺伪物的款冬花非药用部位花梗、根茎进行性状和显微鉴别。结果：明确了款冬花非药用部位花梗、根茎的外观性状特征及显微特征。结论：通过性状及显微鉴别研究，可以对常见掺伪物，款冬花非药用部位花梗及根茎进行鉴别。

Objective: To research the authentication characteristics of non-officinal portions of Farfarae Flos in order to distinguish some traditional Chinese medicines adulterated with non-officinal portions of Farfarae Flos in markets and to provide a scientific basis for the quality control of Farfarae Flos as well as relative traditional Chinese medicinal materials. Methods: On the basis of market research,plant collection and specimen observation,the non-officinal portions,the scape and the rootstock of Farfarae Flos,which might be used as adulterations,were characterized and identified by microscopical methods. Results: The morphological characteristics and microscopic characteristics of the non-officinal portions of Farfarae Flos(the scape and the rootstock)were clarified. Conclusion: The non-officinal portions of Farfarae Flos(the scape and the rootstock)can be identified according to the macroscopical and microscopical characteristics.

1 LUO Xian-rui(罗献瑞), GAO Pei-zhang(高沛璋), CHEN Wei-qiu(陈伟球), et al.Fauna Sinica(中国植物志)[M].Vol 77(1)(第77卷第一分册).Beijing(北京):Science Press(科学出版社), 1999.93
2 XIAO Pei-gen(肖培根).Modern Chinese Materia Medica(新编中药志)[M].Vol 2(第2卷).Beijing(北京):Chemical Industry Press(化学工业出版社), 2002.802
3 ChP(中国药典)[S].2010.Vol Ⅰ(一部):312
4 ZHU Sheng-he(朱圣和).Commodity Science of Chinese Medicinal Materials(中国药材商品学)[M].Beijing(北京):People's Medical Publishing House(人民卫生出版社), 1990.237
5 LIU Xiang(刘香), CAO Juan(曹娟).HPLC determination of rutin in Flos Farfara from different areas(HPLC法测定不同来源款冬花中芦丁的含量)[J].Chin J Pharm Anal(药物分析杂志), 2009, 29(1):134
6 LIU Yu-feng(刘玉峰), YANG Xiu-wei(杨秀伟).RP-HPLC determination of tussilagone in Flos Farfarae(反相高效液相色谱法测定款冬花中的款冬酮含量)[J].Chin J Pharm Anal(药物分析杂志), 2009, 29(1):31
7 ZHANG Wen-yi(张文懿), YANG Tian-shou(杨天寿), WANG Xu-peng(王旭鹏), et al.HPLC determination of chlorogenic acid and rutin contents in Flos Farfarae(HPLC 法测定款冬花中绿原酸和芦丁的含量)[J].Chin J Pharm Anal(药物分析杂志), 2008, 28(12):2106
8 LI Wei(李玮), YANG Xiu-wei(杨秀伟).Simultaneous determination of nine major constituents in Farfarae Flos by HPLC(HPLC法同时测定款冬花中9个主要成分的含量)[J].Chin J Pharm Anal(药物分析杂志), 2012, 32(9):1517.
9 National Institute for the Control of Pharmaceutical and Biological Product(中国药品生物制品检定所).Handbook of Chinese medicinal materials(中药材手册)[M].Beijing(北京):Pelope's Medical Publishing House(人民卫生出版社), 1992.532
10 WANG Shu-li(汪树理), HE Feng-cheng(贺凤成), DONG Jin-ping(董金平), et al.Determination of rutin in crude drugs of Flos Farfarae from Changbai Mountain in different periods(长白山区野生款冬花不同采收期芦丁含量的差异)[J]. Lishizhen Med Mater Med Res(时珍国医国药), 2010, 21(4):842
11 CHEN Zhen(陈震), CHEN Jun(陈君).The cultivation techniques of naturalized Tussilago farfara L.(款冬野生转家种栽培技术)[J].Prim J Chin Mater Med(基层中药杂志), 1999, 13(1):25
12 LIU Yi(刘毅), WANG Yun(王允), QIN Song-yun(秦松云), GAP standard operating procedure for Tussilago farfara L.(中药材款冬花GAP标准操作规程)[J].Lishizhen Med Mater Med Res(时珍国医国药), 2009, 20(11):2861
13 ZHANG Zhi-hong(张志红), GAO Hui-qin(高慧琴), Yang Gui-ping(杨贵平), et al.The cultivation techniques of Flos Farfarae(款冬花栽培技术研究)[J].J Gansu Coll Tradit Chin Med(甘肃中医学院学报), 2012, 29(3):66