TLC-IR法检测降糖中药及保健品中掺入2种双胍类药物

目的：建立降糖中药及保健品中非法添加2种双胍类药物的快速检测方法。方法：采用硅胶GF₂₅₄薄层板，乙酸乙酯-甲醇-冰醋酸（5：6：0.5）为展开剂，展开制备薄层斑点，测其红外光谱。结果：建立的TLC-IR法对降糖中成药及保健品共计6个品种12批次进行检测，其中3种保健品非法添加了双胍类成分。结论：方法简便易行、专属性较强，可用TLC-IR法对降糖中药及保健品中掺入的化学降糖药物进行快速检测。

Objective: To establish a TLC-IR method for rapid detection of 2 kinds of biguanides illegally added into traditional Chinese medicines (TCMs) and health products. Methods: The silica gel GF₂₅₄ thin layer plate was used and a mixture of acetidin-methanol-acetic acid (5:6:0.5) was used as the developing solvent to obtain the sample spot and detect IR spectra. Results: The established TLC-IR method was used to test a total of 6 varieties (12 batches) of antidiabetic Chinese patent medicines and health products,among which 3 health products were detected with illegally added biguanides. Conclusion: This method is simple,rapid and selective,which can be used for rapid detection of illegally added chemical antidiabetic components in antidiabetic TCMs and health products.

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