液质联用技术在天然产物结构鉴定中的应用进展
Progress on application of LC-MS technology in structural identification of the natural products
分类号：
出版年·卷·期（页码）：2013,33 (2):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要：-------------------------------------------------------------------------------------------
天然产物的结构具有多样性与复杂性,因此寻找天然产物快速识别与高效分离的方法是亟待解决的关键问题。液质联用技术将高效液相色谱优秀的分离能力与质谱高灵敏度和高专属性的检测有机地结合在一起,在天然产物研究中发挥着越来越重要的作用。本文综述了液质联用技术近10年来在常见类型的天然产物结构鉴定中的应用情况,并对其发展趋势进行了展望。
-----英文摘要：---------------------------------------------------------------------------------------
Owing to the diversity and complexity of structures of natural products,it is an urgent task to establish rapid identification and effective separation methods as soon as possible.LC-MS technology has combined the excellent separation ability of HPLC,high sensitivity and specificity of mass spectrometer together,and has been playing a more and more important role in the research of natural products.In this paper,the applicability of mass spectrometry for the structural elucidation of ordinary natural products in the past decade was reviewed,and the development trend of LC-MS technology was prospected.
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