多指标综合评分法正交试验优选枳芍散提取工艺

目的: 优选枳芍散复方提取工艺。 方法: 采用正交试验,以芍药苷、柚皮苷、橙皮苷、新橙皮苷含量为指标性成分,考察浸泡时间、溶媒用量和提取次数对提取效果的影响,对实验结果进行综合分析。 结果: 优选出的提取工艺为16倍水浸泡30 min提取2次,每次1 h。 结论: 本试验方法对枳芍散的生产工艺具有一定的指导和参考意义。

Objective: To optimize the extraction technology of Zhishi Shaoyao powder. Methods: The orthogonal test was employed taking the contents of paeoniflorin,naringin,hesperidin and neohesperidin as the indexes and the influences on extraction results of soaking time,solvent dosage and extraction times were investigated,and were analyzed by multi-index comprehensive scoring method. Results: The optimal extracting process was selected as follows: 16 times of water consumption,soak for 30min,extraction twice for 1 hour at each time. Conclusion: The experimental method can serve as a guideline and reference for the production process of Zhishi Shaoyao powder.