气相色谱法测定维生素E软胶囊含量的不确定度评定
GC evaluation of measurement uncertainty for the determination of vitamin E soft cream
分类号：
出版年·卷·期（页码）：2012,32 (4):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要：-------------------------------------------------------------------------------------------
目的: 探讨气相色谱法测定维生素E含量的不确定度评定方法。 方法: 通过分析测量过程,确定并简化不确定度来源;利用气相色谱法测定维生素E的方法验证数据及经验数据,通过统计学方法,量化不确定度分量;计算合成不确定度和扩展不确定度。 结果: 气相色谱法测定维生素E的扩展不确定度为3.6%。 结论: 测量不确定度可用于维生素E的标准限量的制定;测量不确定度的评定方法的确立建立对于药品、保健品、食品及化妆品质量标准的研究具有一定意义。
-----英文摘要：---------------------------------------------------------------------------------------
Objective: To set out the procedure for estimation of measurement uncertainty for the determination of Vitamin E by GC. Methods: Each uncertainty component was evaluated with respect to the significance of its contribution to the overall measurement uncertainty and was expressed as standard uncertainty.All the standard uncertainties were then combined according to the appropriate rules to give a combined standard uncertainty and an expanded standard uncertainty. Results: The expanded standard uncertainties for the GC determination of Vitamin E is 3.6%. Conclusion: Measurement uncertainty is applicable to set the limit of the Vitamin E.The establishment of the methodology for the evaluation of measurement uncertainty is important to the studies of Drugs,Health Products,Foods and cosmetic standards.
-----参考文献：---------------------------------------------------------------------------------------
[1] International Bureau of Weights and Measures,ISO.Guid to the Expression of Uncertainty in Measurement,International Organization for the Standardization.Geneve:ISO,1995.2
[2] National Quality and Technical Supervision.Evaluation and Expression of Uncertainty in Measurement(测量不确定度评定与表示).Beijing(北京):China Metrology Publishing House(中国计量出版社),1999.53
[3] SU Xiao-li(粟晓黎),LI Guan-min(李冠民),JIN Shao-hong(金少鸿).Studies on evaluation of uncertainty for general analysis methods for quality control of drugs(药品检验一般检测项目不确定度评定研究-1.B类评定). Chin J Pharm Anal(药物分析杂志),2005,25(6):699
[4] WEI Hui-zhen(魏惠珍),RAO Yi(饶毅),LI Xin-nan(李新南),et al.Evaluation of measurement uncertainty for the determination of β-caryopyllene in Mujingyou soft capsules by GC internal standard method(气相色谱内标法测定牡荆油胶丸中β-丁香烯含量的不确定度评定).Chin J Pharm Anal(药物分析杂志),2009,29(11):1881
[5] National Quality and Technical Supervision.China National metrological verification(Common Glass Container)(常用玻璃量器计量检定规程).JJG 196-1990.Beijing(北京):Standards Press of China(中国标准出版社),2000.4
欢迎阅读《药物分析杂志》！您是该文第 1543位读者！
