手性配体交换色谱法在手性药物对映体分离分析的应用
Application of CLEC method in separation of chiral drug enantiomers
分类号：
出版年·卷·期（页码）：2010,30 (12):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要：-------------------------------------------------------------------------------------------
手性药物的研究已成为国际新药研究的方向之一。手性药物分析在手性药物研究中作用越来越重要,已成为国际上分析科学中的热点和难点。手性配体交换色谱(CLEC)是直接分离对映异构体的热门方法之一。本文综述了近年来CLEC在手性药物对映体分离分析中的应用,并对这一领域的发展做了展望。
-----英文摘要：---------------------------------------------------------------------------------------
The study on chiral drugs has become one of new directions of new drugs research internationally.Analysis of chiral drugs,with increasing in importance in pharmaceutical research,is now a hot and difficult topic in international analysis science.Chiral ligand-exchange chromatography (CLEC) is one of the most popular methods to direct separation of enantiomers.This paper presents a review of the application research of CLEC in chiral separation of drug enantiomers and a discussion of the developments prospect of this technique.
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