基于分子印迹整体柱的高灵敏度四环素选择电极的研究
Study on highly-sensitive tetracycline selective electrode based on molecular imprinted monolithic column
分类号：
出版年·卷·期（页码）：2010,30 (10):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要：-------------------------------------------------------------------------------------------
目的: 建立高灵敏度测定样品中四环素的电位分析法。 方法: 基于分子印迹整体柱,以四环素-磷钨酸离子缔合物为电活性物质,构建成PVC为基质膜的高灵敏度四环素选择电极,并对电极性能指标进行评价。 结果: 在pH 2~4溶液中,电极的线性范围为1×10-8~1×10-3 mol· L-1,斜率为58.3 mV/pC,检出限为约6×10-9 mol· L-1,精密度和准确度好。 结论: 该电极灵敏度高,选择性好,测定结果准确可靠,可用于药片、人血清、水产品等样品中四环素的含量测定。
-----英文摘要：---------------------------------------------------------------------------------------
Objective: To establish a potentiometric method with high sensitivity to determine tetracycline in various samples. Method: A PVC membrane tetracycline selective electrode with high sensitivity was prepared with the ion-pair of tetracycline-phosphotungstic acid as the electroactive substance,based on molecularly imprinted monolithic column.And then the performance of the electrode was evaluated. Results: The electrode showed a linear Nernst response in the range of 1×10-8-1×10-3 mol· L-1 in a buffer solution of pH 2-4 with a slope of 58.3 mV/pC.The low limit of detection was about 6×10-9 mol· L-1,and the accuracy and precision were good. Conclusion: The proposed electrode is sensitive,selective,accurate and reliable,and thus then can be used for the determination of tetracycline in tablets,human serum and aquatic products,etc.
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