人乳头瘤病毒基因分型检测方法进展

人乳头瘤病毒基因分型检测对子宫颈病变的早期发现、宫颈细胞学异常的评估和管理,病程的进展,高度宫颈上皮内瘤变治疗后的随访,以及人群的流行病学状态和病毒疫苗的研制有重要意义.目前国内外对人乳头瘤病毒进行基因分型的方法主要集中在以靶序列扩增为基础的检测和以信号放大为基础的检测技术两方面,本文就这两方面的检测技术加以叙述。

: It is important that human papillomavirus genotyping pairs on the early detection of cervical lesions,unusual appraisal and the management,the course progress,a high degree of cervical intraepithelial neoplasia follow-up after treatment,as well as the crowd of epidemiological status and virus vaccine is.Now human papillomavirus genotyping will focus on the way to target amplification-based detection and to signal amplification-based detection techniques,this article narrates in these two aspects of detection technologies.