目的：比较2种不同方法提取中药材蒲公英的挥发油化学成分。方法：采用超临界CO2萃取法和石油醚提取法提取蒲公英，并用气相色谱-质谱联用技术对其化学成分进行了分析。结果：从超临界CO2萃取出的蒲公英样品中分离鉴定出26种化学成分，占总质量的7766%；从石油醚提取的蒲公英样品中共鉴定出27种化合物，占总质量的87.23%；超临界CO2萃取法提取的蒲公英样品中酸类物质最多，占总质量的36.4%；而石油醚提取的样品中，除去含量最多的9,12,15-十八碳三烯醛外，则是以酯类物质最多，占总质量的27.68%。结论：2种方法提取的蒲公英样品化学成分各有侧重，与石油醚提取相比，超临界CO2萃取具有提取温度低、溶剂残留少等优点，并可用于提取蒲公英中挥发性和半挥发性酸类成分。
Objective:To compare chemical components of essential oil of Taraxacum mongolicum Hand.Mazz.extracted by two extraction methods.Methods:Samples were extracted from of Taraxacum mongolicum Hand.Mazz.By supercritical CO2 fluid (SFE-CO2) and petroleum ether（PE）.The chemical components of the samples were analyzed by GC-MS.Results:Altogether 26 chemical components were identified from the samples extracted by SFE-CO2,amounting to 77.66% of the total area of the peaks.While in the sample extracted by PE,altogether 27 components were identified，amounting to 87.23% of the total area of the peaks.The acid was the primarily kind of components in the samples extracted by SFE-CO2,amounting to 36.4%,The ester was the main kind of components in the samples extracted by PE，amounting to 27.68%,except 9,12,15-Octadecatrienal.Conclusions:The main components extracted by these two methods were different,compared with PE extraction method,SFE-CO2 method was low extraction temperature,low solvent residual.And SFE-CO2 method can be used to extract the volatile acids and semi-volatile acids of Taraxacum mongolicum Hand.Mazz.
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