双氯芬酸钠缓释片体外实时释放的研究___
Studies on the process analysis for dissolution of diclofenac sodium sustained release tablets
分类号:
出版年·卷·期(页码):2009,29 (11):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
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-----英文摘要:---------------------------------------------------------------------------------------
Objective: To establish a processing analysis method for the dissolution of declofenac sodium sustained release tablets . Method: The release procession test of 3 batches by using FODT-601 fiber-optic real time dissolution test system, and comparing with the result by using ChP 2002 supplement dissolution method. Results: The recoveries of this way is 99.4%-100.6%. The cumulation release rate of declofenac sodium sustained release tablets measured by this system at 2, 6 and 12 hours,respectively had no significant difference compared with the test results of ChP dissolution method(P>0.05). Conclution: Fiber-optic medicine dissolution/release rate process monitoring method can determine effectively the release rate of medicine.
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