反相HPLC法测定大鼠血浆中17-烯丙胺基-17-脱甲基格尔德霉素及其代谢产物17-氨基-17-脱甲基格尔德霉素___
RP-HPLC Measurement of 17-Allylamino-17-Demethoxygeldana-mycin and Its Active Metabolite 7-Amino-17-Demethoxygeldanamycin in Rat Plasma
分类号:
出版年·卷·期(页码):2005,25 (10):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
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To establish a sensitive RP-HPLC method for determining the concentration of 17-allylamino-17-demethoxygeldanamycin (17AAG) and 17-amino-17-demethoxygeldanamycin (17AG) in rat plasma.Methods: The plasma samples were extracted with ethyl acetate.The separa
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