抗肿瘤药物依托泊甙的质量研究___
Studies on the Quality of Antitumor Agent Etoposide VP16
分类号:
出版年·卷·期(页码):1994,14 (5):0-0
DOI:
10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------
本文采用溶剂重结晶法精制抗肿瘤药物依托泊甙(etooposide),精制前后用UV、IR及TLC进行检查;用相溶度分析法和高效液相色谱法
测定含量;用热分析方法测定了依托泊甙的热特征。精制后的依托泊甙纯度达99%以上。
-----英文摘要:---------------------------------------------------------------------------------------
The purified etoposide was investigated under different conditions with TLC, UV, IR,DSC and TG for qualitative analysis.
The purity of recrystallized etoposide is better than 99% as determined by phase solubility analysis and HPLC.
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