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刊物信息

期刊名称:药物分析杂志
主管单位:中国科学技术协会
主办单位:中国药学会
承办:中国食品药品检定研究院
主编:金少鸿
地址:北京天坛西里2号
邮政编码:100050
电话:010-67012819,67058427
电子邮箱:ywfx@nifdc.org.cn
国际标准刊号:ISSN 0254-1793
国内统一刊号:CN 11-2224/R
邮发代号:2-237
 

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云南马钱与马钱的比较研究

Comparative study on Strychni Pierrianae Semen and Strychni Semen

分类号:
出版年·卷·期(页码):2014,34 (7):0-0
DOI: 10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------

目的:对云南马钱与马钱进行比较研究。 方法:运用高效液相色谱法、薄层色谱法、显微鉴别法、特征图谱研究等多种方法对云南马钱和马钱从原植物形态,种子性状、显微特征、薄层色谱及高效液相色谱进行比较。 结果:云南马钱与马钱的植物基原,种子的性状、液相色谱特征具明显区别,显微特征与薄层色谱无明显差异,马钱子碱与士的宁含量存在差异。 结论:采用植物形态、药材性状、液相色谱图谱特征可以鉴别云南马钱与马钱。

-----英文摘要:---------------------------------------------------------------------------------------

Objective: To conduct a comparative study on Strychni Pierrianae Semen and Strychni Semen. Methods: The methods of TLC,HPLC,LC fingerprint and microscopic identification were applied to compare the two medical materials,from the aspects of the original plant morphology,seed characteristics,microscopic characteristics,TLC result and HPLC result. Results: There were obvious differences between Strychni Pierrianae Semen and Strychni Semen in the original plant morphology,seed characteristics and HPLC result.However,there was no remarkable difference in microscopic characteristics and TLC result of these two medical materials.Meanwhile,there was some difference in the contents of brucine and strychnine. Conclusion: Strychni Pierrianae Semen and Strychni Semen can be distinguished by the plant morphology,crude drugs characteristics and HPLC fingerprint features.

-----参考文献:---------------------------------------------------------------------------------------
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[6] LI Ping(李萍).Pharmacognosy(生药学)[M].2nd ed(第2版).Beijing(北京):China Medical Science and Technology Press(中国医药科技出版社),2010:305
[7] XIA L,BAI LP,CHU C,et al.Authentication of the 31 species of toxic and potent Chinese materia medica (T/PCMM) by microscopic technique,Part 2:three species of seed T/PCMM[J].Microsc Res Tech,2008,71:325
[8] ChP 2010.VolⅠ(中国药典2010年版.一部)[S].2010:47
[9] ZHANG Ke-liang(张克良),HE Ya-wei(何亚维).The alkaloid content determination of Strychni Semen from various places(不同地区马钱子生物碱含量测定) [J].Primary J Chin Mater Med(基层中医药杂志),1998,12(1):24
[10] GUO Wen-sheng(郭文生),DING Chao(丁超).Study of new method of selective separation of brucine in Maqianzi(从马钱子中选择分离马钱子碱新方法的研究) [J].Nat Prod Res Dev(天然产物研究与开发),2004,16(2):97
[11] WANG Zhao-hong(王朝红),GUO De-an(果德安),HU Chun-hua(胡春华).Determination of brucine and strychnine in human blood by reversed-phase high performance liquid chromatography(反相高效液相色谱法测定全血中马钱子碱和士的宁的含量)[J].Chin J Chromatogr(色谱),2003,21(4):382

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