顺铂在玻碳电极上的电化学行为及其测定的研究

目的: 研究顺铂在玻碳电极上的电化学行为及其测定方法。 方法: 循环伏安法(CV)和差分脉冲伏安法(DPV)。 结果: 顺铂在玻碳电极上有一对准可逆氧化还原峰,氧化峰电位E_pa与还原峰电位E_pc分别为0.78,0.3 V,△E=0.48 V, I_pa/I_pc=4.30。在优化条件下,顺铂的氧化峰电流与其浓度在6.54×10^-5~3.03×10^-4 mol·L^-1范围内成良好的线性关系(r=0.9978),检出限为3.9×10^-5 mol·L^-1。 结论: 本方法操作简便,准确可靠,灵敏度高,可用于顺铂含量的直接测定。

Objective: To investigated the electrochemical behavior and determination of cisplatin at glassy carbon electrode. Methods: Cyclic voltammetry and differential pulse voltammetry. Results: One pair of quasi-reversible redox peaks of cisplatin was obtained at glassy carbon electrode by cyclic voltammetry with 0.78 V of E_pa and 0.3 V of E_pc,△E=0.48 V,and I_pa/I_pc=4.30.Under optimal condition,the oxidization peak was linearly related to the concentration of cisplatin in the rang of 6.54×10^-5-3.03×10^-4 mol·L^-1 with the detection limit of 3.9×10^-5 mol·L^-1. Conclusion: This method was convenient,accurate,credible and sensitive,it can be used in the determination of cisplatin.